Health Trends

Maryland Department of Health releases human monkeypox vaccination pre-registration system

Baltimore, MD – The Maryland Department of Health (MDH) today released the Maryland Statewide Human Monkeypox (MPX) Vaccination Pre-Registration System enabling Marylanders to sign up to be notified when an MPX vaccine opportunity becomes available.

“This pre-registration system is another step to ensure that Marylanders can access the tools to stay protected from human monkeypox,” said MDH Secretary Dennis R. Schrader. “Keeping impacted residents healthy and safe remain our top priority.”

The new vaccine pre-registration system will be available 24 hours a day, 7 days a week. People who register through the system and are determined to be eligible for the vaccine will receive an email invitation to make an appointment through their local health department. 

To date, Maryland has received 14,539 vials of JYNNEOS vaccine from the federal government. MDH has worked closely with local health departments to implement intradermal injections, meaning three to five doses from each vial. Those vaccines are available to any eligible individual in any jurisdiction. The pre-registration system continues MDH and local health department efforts to provide easier access for eligible Marylanders to opt-in and mitigate the spread of monkeypox. 

The vaccination pre-registration system is intended for Maryland residents who meet one of the following criteria:

  • Self-identified close contact of a person with MPX 
  • An impacted community member with potential MPX exposures in the prior 2 weeks

Vaccinations to prevent MPX disease are free. Pre-registration is for the first MPX vaccine dose only. Subsequent doses will be coordinated for each individual by the first dose provider.

MDH urges interested Maryland residents to still pre-register even if they do not meet the current vaccination eligibility criteria. If eligibility expands, people who have already pre-registered will be notified of available appointments.

Anyone who has monkeypox symptoms should contact their health care provider.  People without a provider or insurance should contact their local health department.

For additional monkeypox resources, including fact sheets and FAQs, visit

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